SCHEMBL23930993

SCHEMBL23930993

CCn1c(C=O)nc(C)c1C(=O)NC1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 4/20 0.39
POLR1A O95602 1/20 0.38
USP30 Q70CQ3 4/20 0.37
GABRA5 P31644 2/20 0.37
PARP1 P09874 2/20 0.37
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
ADORA2A P29274 2/20 0.36
ADORA2B P29275 2/20 0.36
HDAC4 P56524 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21880092 0.86 USP30 (0.41) POLR1AUSP30GABRA5PARP1ADORA2A
SCHEMBL21880058 0.85 KDM4E (0.33)
SCHEMBL21880034 0.83 ADORA2A (0.38) POLR1AUSP30GABRA5PARP1ADORA2A
SCHEMBL21879937 0.82 HDAC4 (0.39) POLR1AUSP30GABRA5PARP1ADORA2A
SCHEMBL23931020 0.79 GABRA5 (0.36) POLR1AUSP30GABRA5PARP1LMNA
SCHEMBL21879973 0.79 USP30 (0.39) PIK3CDPOLR1AUSP30GABRA5PARP1
SCHEMBL23930977 0.77 USP30 (0.44) POLR1AUSP30GABRA5PARP1ADORA2A
SCHEMBL23930984 0.77 USP30 (0.40) POLR1AUSP30PARP1ADORA2AADORA2B
SCHEMBL21879895 0.76 USP30 (0.39) POLR1AUSP30PARP1ADORA2AADORA2B
SCHEMBL29902371 0.76 USP30 (0.47) POLR1AUSP30GABRA5PARP1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
EP-4067343-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
WO-2021215545-A1 ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C TAIHO PHARMACEUTICAL CO., LTD. (JP) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB PIK3CD 3736/4885POLR1A 751/4885USP30 3423/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 PIK3CD 3742/4885POLR1A 747/4885USP30 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.