Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 10/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933226 | 1.00 | DGAT1 (0.39) | DGAT1HSD11B1HSD11B2EPHX1HPGD | |
| SCHEMBL23933228 | 1.00 | DGAT1 (0.39) | DGAT1HSD11B1HSD11B2EPHX1HPGD | |
| SCHEMBL23992105 | 0.85 | THRB (0.36) | EPHX1 | |
| SCHEMBL23992101 | 0.85 | HSD11B1 (0.38) | HSD11B1HSD11B2EPHX1 | |
| SCHEMBL23992210 | 0.84 | SCN9A (0.32) | EPHX1 | |
| SCHEMBL23992080 | 0.82 | SCN9A (0.34) | HSD11B1 | |
| SCHEMBL23992079 | 0.82 | EPHX1 (0.44) | HSD11B1EPHX1 | |
| SCHEMBL23992082 | 0.79 | MEN1 (0.34) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL23933225 | 0.78 | ALDH1A1 (0.33) | HSD11B1 | |
| SCHEMBL23992016 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |