Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385711 | 0.79 | L3MBTL1 (0.36) | ALDH1A1NPC1POLBHTTGAA | |
| SCHEMBL385712 | 0.79 | L3MBTL1 (0.36) | ALDH1A1NPC1POLBHTTGAA | |
| SCHEMBL383047 | 0.78 | L3MBTL1 (0.39) | ALDH1A1MEN1KMT2AHTTGAA | |
| SCHEMBL383046 | 0.78 | L3MBTL1 (0.39) | ALDH1A1MEN1KMT2AHTTGAA | |
| SCHEMBL1457331 | 0.78 | NOS2 (0.38) | MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL1457333 | 0.78 | NOS2 (0.38) | MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7403659 | 0.75 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2KDM4EHRH3 | |
| SCHEMBL7403657 | 0.75 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2KDM4EHRH3 | |
| SCHEMBL14706862 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ANPC1ACHE | |
| SCHEMBL15794748 | 0.74 | CHRM5 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242586-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| EP-4138875-A1 | RAS INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021217019-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242586-A1 | RAS INHIBITORS AND USES THEREOF | KRAS, NRAS, HRAS | ALDH1A1 4073/4885MEN1 393/4885KMT2A 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.