SCHEMBL385711

SCHEMBL385711

CC(NN1CCCC1)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
CHRM1 P11229 1/20 0.35
RAB9A P51151 2/20 0.34
MME P08473 1/20 0.34
HTT P42858 1/20 0.33
TP53 P04637 2/20 0.32
LTA4H P09960 2/20 0.32
NPC1 O15118 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
ALOX12 P18054 1/20 0.31
NFKB1 P19838 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL385712 1.00 L3MBTL1 (0.36) L3MBTL1CHRM1RAB9AMMEHTT
SCHEMBL383047 0.98 L3MBTL1 (0.39) L3MBTL1CHRM1RAB9AMMEHTT
SCHEMBL383046 0.98 L3MBTL1 (0.39) L3MBTL1CHRM1RAB9AMMEHTT
Alanine SCHEMBL4954723 0.92 LTA4H (0.35) L3MBTL1CHRM1RAB9AMMEHTT
Glycine SCHEMBL4955873 0.89 GLRA1 (0.36) L3MBTL1CHRM1MMELTA4HDPP7
Threonine SCHEMBL4955781 0.86 SLC7A5 (0.36) LTA4HDPP7
Serine SCHEMBL4956028 0.84 DPP7 (0.40) L3MBTL1CHRM1MMELTA4HDPP7
Pyrrole SCHEMBL28327955 0.84 L3MBTL1 (0.38) L3MBTL1HTTNPC1ALDH1A1GAA
SCHEMBL15794748 0.81 CHRM5 (0.41) RAB9APOLB
SCHEMBL15794935 0.81 CHRM5 (0.41) RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2722051-A1 Monomethylvaline compounds having phenylalanine side-chain modifications at the C-terminus Seattle Genetics, Inc. (US) 2014-04-23 EP claimed
WO-2010132580-A2 METHODS OF INHIBITING THE GHRELIN/GROWTH HORMONE SECRETATOGUE RECEPTOR PATHWAY AND USES THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2010-11-18 WO claimed
US-20090018086-A1 Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus SEATTLE GENETICS, INC. (US) 2009-01-15 US claimed
US-7439226-B2 Serine protease inhibitors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2008-10-21 US claimed
EP-1917020-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS Seattle Genetics, Inc. (US) 2008-05-07 EP claimed
WO-2007055578-A1 CYCLIC ANTIMICROBIAL PEPTIDES DERIVED FROM LACTOFERRIN LEIDS UNIVERSITAIR MEDISCH CENTRUM (NL) 2007-05-18 WO claimed
EP-1761554-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME Biosource Pharm, Inc. (US) 2007-03-14 EP claimed
WO-2007008603-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2007-01-18 WO claimed
WO-2006083317-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM, INC. (US) 2006-08-10 WO claimed
WO-2006043933-A1 SERINE PROTEASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-27 WO claimed
US-20050130883-A1 Serine protease inhibitors THE GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2005-06-16 US claimed
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS UNIV MICHIGAN (US) 2026-02-26 US disclosed
EP-4680108-A1 PEPTIDE MULTIMER PRODUCTS AND METHODS The Regents of The University of Michigan (US) 2026-01-21 EP disclosed
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-21 US disclosed
US-20250263685-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION 2025-08-21 US disclosed
WO-2006083317-A9 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM INC (US) 2007-03-01 WO disclosed
WO-2007008603-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2007-01-18 WO disclosed
WO-2006083317-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM, INC. (US) 2006-08-10 WO disclosed
WO-2006043933-A1 SERINE PROTEASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-27 WO disclosed
US-20050130883-A1 Serine protease inhibitors THE GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS TP53, TP53BP1, DDIT3 L3MBTL1 355/4885CHRM1 3749/4885RAB9A 2700/4885
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS ERBB2, EGFR, ERBB3 L3MBTL1 3066/4885CHRM1 4702/4885RAB9A 2164/4885
US-20090018086-A1 Monomethylvaline Compounds Having Phenylalanine Side-Chain Replacements at the C-Terminus MMAB, DNPEP, MARCKS L3MBTL1 75/4885CHRM1 2969/4885RAB9A 2318/4885
US-20250263685-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA L3MBTL1 1472/4885CHRM1 4449/4885RAB9A 757/4885
US-20050130883-A1 Serine protease inhibitors PRSS1, TASP1, METAP1 L3MBTL1 1590/4885CHRM1 4600/4885RAB9A 2366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.