Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933777 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TAAR1CNR1MASP2KMT2A | |
| SCHEMBL23933774 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TAAR1CNR1MASP2KMT2A | |
| SCHEMBL23933844 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TAAR1CNR1MASP2KMT2A | |
| SCHEMBL23933782 | 0.84 | METAP2 (0.44) | ALDH1A1CNR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23933785 | 0.84 | METAP2 (0.44) | ALDH1A1CNR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23933788 | 0.84 | METAP2 (0.44) | ALDH1A1CNR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23933759 | 0.84 | MASP2 (0.42) | ALDH1A1TAAR1CNR1MASP2KMT2A | |
| SCHEMBL23933765 | 0.84 | MASP2 (0.42) | ALDH1A1TAAR1CNR1MASP2KMT2A | |
| SCHEMBL23933762 | 0.84 | MASP2 (0.42) | ALDH1A1TAAR1CNR1MASP2KMT2A | |
| SCHEMBL23933749 | 0.77 | DPP4 (0.38) | ALDH1A1TAAR1CNR1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |