Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933782 | 1.00 | METAP2 (0.44) | METAP2METAP1TSHRMMP8CNR2 | |
| SCHEMBL23933788 | 1.00 | METAP2 (0.44) | METAP2METAP1TSHRMMP8CNR2 | |
| SCHEMBL23933752 | 0.86 | DPP4 (0.38) | KMT2ASMN1; SMN2ALDH1A1CNR1MEN1 | |
| SCHEMBL23933882 | 0.86 | DPP4 (0.38) | KMT2ASMN1; SMN2ALDH1A1CNR1MEN1 | |
| SCHEMBL23933754 | 0.86 | DPP4 (0.38) | KMT2ASMN1; SMN2ALDH1A1CNR1MEN1 | |
| SCHEMBL23933749 | 0.86 | DPP4 (0.38) | KMT2ASMN1; SMN2ALDH1A1CNR1MEN1 | |
| SCHEMBL23933801 | 0.85 | MMP2 (0.43) | ANPEP | |
| SCHEMBL23933799 | 0.85 | MMP2 (0.43) | ANPEP | |
| SCHEMBL23933794 | 0.85 | MMP2 (0.43) | ANPEP | |
| SCHEMBL23933768 | 0.84 | ALDH1A1 (0.43) | METAP2HTTKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |