Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.43 |
| ▸ | CTSV | O60911 | 10/20 | 0.43 |
| ▸ | CTSS | P25774 | 10/20 | 0.43 |
| ▸ | CTSK | P43235 | 8/20 | 0.43 |
| ▸ | CTSB | P07858 | 8/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933861 | 1.00 | CTSL (0.43) | CTSLCTSVCTSSCTSKCTSB | |
| SCHEMBL23933860 | 1.00 | CTSL (0.43) | CTSLCTSVCTSSCTSKCTSB | |
| SCHEMBL23933796 | 0.89 | PNMT (0.43) | CTSLCTSVCTSSCTSKCTSB | |
| SCHEMBL23933798 | 0.89 | PNMT (0.43) | CTSLCTSVCTSSCTSKCTSB | |
| SCHEMBL23933793 | 0.89 | PNMT (0.43) | CTSLCTSVCTSSCTSKCTSB | |
| SCHEMBL23933856 | 0.79 | PPARA (0.54) | PPARGPPARAPNMT | |
| SCHEMBL23933859 | 0.79 | PPARA (0.54) | PPARGPPARAPNMT | |
| SCHEMBL23933762 | 0.78 | MASP2 (0.42) | ALDH1A1TAAR1MAPTCNR1 | |
| SCHEMBL23933765 | 0.78 | MASP2 (0.42) | ALDH1A1TAAR1MAPTCNR1 | |
| SCHEMBL23933763 | 0.76 | SRR (0.50) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |