Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.33 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18417805 | 0.83 | TDP1 (0.38) | ALDH1A1HPGDSMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL27821688 | 0.79 | GAA (0.53) | ALDH1A1HPGDSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL13856244 | 0.77 | ALDH1A1 (0.37) | ALDH1A1HPGDHSP90AA1CYP3A4ALOX15 | |
| SCHEMBL25937859 | 0.74 | PTGS1 (0.51) | ALDH1A1SMN1; SMN2TP53HSD17B10TDP1 | |
| SCHEMBL9735709 | 0.74 | CYP1A2 (0.43) | ALDH1A1SMN1; SMN2TSHRTDP1L3MBTL1 | |
| SCHEMBL13169883 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDHSP90AA1THRBTDP1 | |
| SCHEMBL31190191 | 0.74 | TRPA1 (0.52) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL599002 | 0.74 | TRPA1 (0.52) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21351250 | 0.74 | SLC18A1 (0.35) | ALDH1A1HPGDSMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL15850424 | 0.74 | POLB (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130023-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | PSY THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| EP-3086815-B1 | SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES | ZYMEWORKS INC (CA) | 2022-02-09 | — | — | EP | disclosed |
| EP-3087091-B1 | VAR2CSA-DRUG CONJUGATES | ZYMEWORKS INC (CA) | 2021-10-20 | — | — | EP | disclosed |