Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879606 | 0.89 | HTT (0.62) | SLC6A4HTTSMN1; SMN2AOC3TAAR1 | |
| SCHEMBL20172543 | 0.80 | SLC6A4 (0.58) | SLC6A4HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12339254 | 0.80 | HTT (0.57) | SLC6A4HTTSMN1; SMN2AOC3TAAR1 | |
| SCHEMBL13166017 | 0.80 | SLC6A4 (0.58) | SLC6A4HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13166015 | 0.80 | SLC6A4 (0.58) | SLC6A4HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21323940 | 0.80 | SLC6A4 (0.62) | SLC6A4AOC3TAAR1L3MBTL1POLB | |
| SCHEMBL18557398 | 0.79 | HTT (0.56) | SLC6A4HTTSMN1; SMN2AOC3TAAR1 | |
| SCHEMBL28347286 | 0.79 | ALDH1A1 (0.60) | HTTSMN1; SMN2MAPK1L3MBTL1POLB | |
| SCHEMBL28347287 | 0.79 | ALDH1A1 (0.60) | HTTSMN1; SMN2MAPK1L3MBTL1POLB | |
| SCHEMBL4865413 | 0.79 | SLC6A4 (0.61) | SLC6A4HTTSMN1; SMN2TAAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369867-A1 | LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY | NUTCRACKER THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | US | disclosed |
| US-20210324002-A1 | TERTIARY AMINO LIPIDATED CATIONIC PEPTIDES FOR NUCLEIC ACID DELIVERY | NUTCRACKER THERAPEUTICS, INC. (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369867-A1 | LIPID NANOPARTICLE FORMULATIONS COMPRISING LIPIDATED CATIONIC PEPTIDE COMPOUNDS FOR NUCLEIC ACID DELIVERY | PHOSPHO1, PLIN3, CETP | SLC6A4 2707/4885HTT 1115/4885SMN1; SMN2 2989/4885 |
| US-20210324002-A1 | TERTIARY AMINO LIPIDATED CATIONIC PEPTIDES FOR NUCLEIC ACID DELIVERY | LNPEP, SLC7A1, APLNR | SLC6A4 1957/4885HTT 1069/4885SMN1; SMN2 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.