Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278613 | 0.84 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23935770 | 0.83 | L3MBTL1 (0.53) | NPC1RAB9ASMN1; SMN2THRATHRB | |
| SCHEMBL15076021 | 0.83 | THRA (0.61) | NPC1RAB9ASMN1; SMN2THRATHRB | |
| SCHEMBL28407075 | 0.82 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2THRATHRB | |
| SCHEMBL5311917 | 0.81 | HDAC8 (0.66) | NPC1MEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL1121702 | 0.80 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18909755 | 0.78 | HMGCR (0.45) | NPC1RAB9ASMN1; SMN2PKMFFAR1 | |
| SCHEMBL28062364 | 0.78 | HTR7 (0.59) | HTR7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8128239 | 0.77 | THRA (0.46) | NPC1RAB9ATHRATHRBMEN1 | |
| SCHEMBL22039528 | 0.77 | DRD2 (0.47) | NPC1RAB9ASMN1; SMN2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366330-A | A FLUOROPHENOL CAPABLE OF BEING REACTED WITH AN ARYL OR CYCLOALKYL CARBOXYLIC ACID TO PRODUCT AN ESTER | BCH CHEMICALS LIMITED (GB) | 1982-12-28 | — | — | US | disclosed |