Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382747 | 0.81 | PTGDR2 (0.73) | L3MBTL1TDP1PTGDR2KMT2AMEN1 | |
| SCHEMBL9787048 | 0.75 | L3MBTL1 (0.73) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9787116 | 0.73 | L3MBTL1 (0.65) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5770727 | 0.73 | L3MBTL1 (0.60) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5042464 | 0.73 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL24488994 | 0.71 | PTGDR2 (0.60) | L3MBTL1TDP1PTGDR2KMT2AMEN1 | |
| SCHEMBL6905536 | 0.70 | TSHR (0.42) | ALDH1A1MAPTKDM4ELMNAMAPK1 | |
| SCHEMBL5770310 | 0.70 | L3MBTL1 (0.53) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9644385 | 0.69 | TDP1 (0.65) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10260277 | 0.69 | ROCK2 (0.73) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401276-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | Eisai R&D Management Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |
| EP-0737187-A1 | BENZOXAZINE DERIVATIVES, METHODS FOR OBTAINING SAME AND THEIR USE AS DRUGS | Laboratoires Pharmascience (FR) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018114-A1 | BENZOXAZINE DERIVATIVES, METHODS FOR OBTAINING SAME AND THEIR USE AS DRUGS | LABORATOIRES PHARMASCIENCE (FR) | 1995-07-06 | — | — | WO | disclosed |