Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382747 | 0.88 | PTGDR2 (0.73) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL24490618 | 0.81 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1TDP1LMNA | |
| SCHEMBL354835 | 0.76 | PTGDR2 (1.00) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL1752352 | 0.74 | PTGDR2 (0.72) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL1287954 | 0.74 | PTGDR2 (0.72) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL31428467 | 0.74 | PTGDR2 (0.72) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL9695894 | 0.74 | PTGDR2 (0.72) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL9979665 | 0.73 | PTGDR2 (0.69) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL1948329 | 0.72 | PTGDR2 (0.68) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL20165417 | 0.72 | L3MBTL1 (0.55) | PTGDR2ALDH1A1SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |