Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200775 | 0.88 | PAOX (0.59) | CYP2C9CYP2C19PAOXDNM1TDP1 | |
| SCHEMBL13926927 | 0.86 | PAOX (0.58) | CYP2C9CYP2C19PAOXTDP1KDM4E | |
| SCHEMBL1806852 | 0.81 | MAOA (0.37) | CYP2C9CYP2C19PAOXTDP1KDM4E | |
| SCHEMBL29256117 | 0.80 | CYP2C9 (0.48) | CYP2C9CYP2C19PAOXANPEPDNM1 | |
| SCHEMBL28709277 | 0.80 | CYP2C9 (0.48) | CYP2C9CYP2C19PAOXANPEPDNM1 | |
| SCHEMBL16638631 | 0.78 | MAOA (0.36) | CYP2C9CYP2C19PAOXTDP1KDM4E | |
| SCHEMBL23792746 | 0.77 | KMT2A (0.52) | CYP2C9CYP2C19PAOXANPEPDNM1 | |
| SCHEMBL177426 | 0.76 | — | — | |
| SCHEMBL344526 | 0.75 | CYP2C9 (0.72) | CYP2C9CYP2C19PAOXANPEPTDP1 | |
| SCHEMBL22571031 | 0.75 | DNM1 (0.58) | DNM1ALDH1A1HTTSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |