SCHEMBL23937115

SCHEMBL23937115

c1ccc(-c2cc(-n3c4ccccc4c4c5c6ccccc6n(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)c5ccc43)ccn2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
COMT P21964 1/20 0.38
ASIC3 Q9UHC3 1/20 0.37
RAC2 P15153 1/20 0.35
RAC3 P60763 1/20 0.35
CDC42 P60953 1/20 0.35
RAC1 P63000 1/20 0.35
KMT2A Q03164 3/20 0.34
IL1R1 P14778 1/20 0.34
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
PTK2B Q14289 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16999747 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMCOMTASIC3
SCHEMBL23805771 0.87 L3MBTL1 (0.47) L3MBTL1KDM4EATMRAC2RAC3
SCHEMBL30376996 0.87 L3MBTL1 (0.50) L3MBTL1KDM4EATMCOMTASIC3
SCHEMBL19972423 0.87 L3MBTL1 (0.50) L3MBTL1KDM4EATMCOMTASIC3
SCHEMBL23937116 0.85 MAPT (0.36) L3MBTL1KDM4EATMCOMTASIC3
SCHEMBL23805768 0.84 KDM4E (0.53) L3MBTL1KDM4EATMRAC2RAC3
SCHEMBL18124845 0.84 L3MBTL1 (0.56) L3MBTL1KDM4EATMRAC2RAC3
SCHEMBL18593828 0.84 L3MBTL1 (0.56) L3MBTL1KDM4EATMRAC2RAC3
SCHEMBL24677370 0.84 L3MBTL1 (0.56) L3MBTL1KDM4EATMRAC2RAC3
SCHEMBL17245449 0.84 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210323968-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210323968-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ECI1, NDUFS3, NDUFV1 L3MBTL1 2949/4885KDM4E 3164/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.