Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.62 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547038 | 0.88 | KMT2A (0.56) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| Hydrochloric Acid SCHEMBL27396597 | 0.86 | KMT2A (0.55) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL2391274 | 0.84 | PTGER1 (0.44) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL2393760 | 0.84 | CHRM1 (0.56) | PTGER4PTGER3PTGER1PTGER2ACLY | |
| SCHEMBL2392257 | 0.84 | ICMT (0.54) | PTGER4PTGER3PTGER1PTGER2ICMT | |
| SCHEMBL7311559 | 0.82 | BCAT2 (0.50) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL9890742 | 0.80 | MTNR1A (0.50) | KMT2AICMTMAPK1 | |
| SCHEMBL2391627 | 0.80 | RORB (0.51) | ICMT | |
| SCHEMBL9890746 | 0.80 | PTGER1 (0.48) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL28451933 | 0.79 | PTGER4 (0.60) | PTGER4PTGER3PTGER1PTGER2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084176-B2 | N-arylphenylacetamide derivatives and medicinal compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |