Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631710 | 0.73 | KAT2B (0.41) | — | |
| SCHEMBL19674405 | 0.67 | — | — | |
| SCHEMBL23937837 | 0.66 | — | — | |
| SCHEMBL23937896 | 0.60 | HTR2A (0.33) | — | |
| SCHEMBL20674214 | 0.55 | CCNA2 (0.38) | — | |
| SCHEMBL24701731 | 0.54 | RAB9A (0.36) | — | |
| SCHEMBL14788205 | 0.54 | RAB9A (0.33) | — | |
| SCHEMBL11981381 | 0.54 | MAOA (0.39) | — | |
| SCHEMBL62597 | 0.52 | — | — | |
| SCHEMBL23937643 | 0.52 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |