Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23937644 | 0.82 | ALDH1A1 (0.40) | CREBBPADRA2AADRA1AUSP2ALDH1A1 | |
| SCHEMBL20674216 | 0.69 | BRD4 (0.41) | KAT2BBAZ2BGAABRD4 | |
| SCHEMBL21959624 | 0.69 | KAT2B (0.38) | KAT2BBAZ2BGAABRD4 | |
| SCHEMBL20631710 | 0.66 | KAT2B (0.41) | KAT2BBAZ2BALDH1A1GAABRD4 | |
| SCHEMBL1515397 | 0.66 | BAZ2B (0.38) | KAT2BBAZ2BCREBBPALDH1A1BRD4 | |
| SCHEMBL29133954 | 0.60 | MTNR1B (0.46) | KAT2BBAZ2BGAA | |
| SCHEMBL30184412 | 0.60 | MTNR1B (0.46) | KAT2BBAZ2BGAA | |
| SCHEMBL22289913 | 0.60 | GFER (0.46) | USP2ALDH1A1MAPK1 | |
| SCHEMBL25104147 | 0.59 | MAOA (0.42) | KAT2BBAZ2BALDH1A1GAABRD4 | |
| SCHEMBL19953833 | 0.59 | HDAC2 (0.33) | KAT2BBAZ2BALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |