Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20674243 | 0.82 | LCK (0.41) | — | |
| SCHEMBL20674244 | 0.79 | CHRM1 (0.31) | CHRM1BRD4 | |
| SCHEMBL20674062 | 0.77 | PDE2A (0.43) | BAZ2BBRD4 | |
| SCHEMBL23937850 | 0.77 | BAZ2B (0.40) | BAZ2BHSD17B10BRD4 | |
| SCHEMBL23937851 | 0.75 | TLR7 (0.35) | BAZ2BCHRM1HSD17B10BRD4 | |
| SCHEMBL23937755 | 0.72 | FTO (0.36) | BRD4 | |
| SCHEMBL20674247 | 0.70 | HRH4 (0.34) | — | |
| SCHEMBL23937675 | 0.70 | TUBB4A (0.39) | BRD4 | |
| SCHEMBL22204309 | 0.67 | RXFP1 (0.40) | — | |
| SCHEMBL19932639 | 0.67 | KMT2A (0.43) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |