Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481706 | 0.75 | CHRNA7 (0.35) | TDP1ACHEALOX5CHRNA7TSHR | |
| SCHEMBL30949389 | 0.71 | CHRNA7 (0.42) | TDP1STAT3ACHEALOX5CHRNA7 | |
| SCHEMBL4671829 | 0.68 | CYP2A6 (0.39) | TDP1CYP2A6STAT3ACHEALOX5 | |
| SCHEMBL138151 | 0.68 | TSHR (0.46) | TDP1CYP2A6ACHETSHRALDH1A1 | |
| SCHEMBL17086707 | 0.67 | ALDH1A1 (0.39) | TDP1STAT3ACHEALOX5CHRNA7 | |
| SCHEMBL17399520 | 0.67 | ALDH1A1 (0.39) | TDP1STAT3ACHEALOX5CHRNA7 | |
| SCHEMBL20706326 | 0.67 | CHRNA7 (0.39) | TDP1STAT3ACHEALOX5CHRNA7 | |
| SCHEMBL17086708 | 0.67 | ALDH1A1 (0.39) | TDP1STAT3ACHEALOX5CHRNA7 | |
| SCHEMBL28953183 | 0.67 | KEAP1 (0.39) | TSHRALDH1A1LMNASMN1; SMN2KEAP1 | |
| Tert-Butyl Formate SCHEMBL28146840 | 0.66 | TDP1 (0.59) | TDP1CYP2A6ACHETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322388-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210322388-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | TDP1 4138/4885CYP2A6 4287/4885STAT3 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.