SCHEMBL32682142

SCHEMBL32682142

Clc1cc2ccc(-c3ccccc3)cc2cn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.48
ESR2 Q92731 3/20 0.48
CYP11B1 P15538 2/20 0.45
CYP11B2 P19099 2/20 0.45
CYP17A1 P05093 1/20 0.44
CYP19A1 P11511 1/20 0.44
CLK4 Q9HAZ1 2/20 0.44
MAP4K4 O95819 1/20 0.44
TYK2 P29597 1/20 0.44
MINK1 Q8N4C8 1/20 0.44
SRPK1 Q96SB4 1/20 0.44
BACE1 P56817 1/20 0.43
FGFR1 P11362 1/20 0.43
DYRK3 O43781 1/20 0.43
CLK1 P49759 1/20 0.43
CLK2 P49760 1/20 0.43
CLK3 P49761 1/20 0.43
GSK3B P49841 1/20 0.43
CDK5 Q00535 1/20 0.43
DYRK1A Q13627 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23705771 0.93 CLK4 (0.51) ESR1ESR2CYP11B1CYP11B2CYP17A1
SCHEMBL14244848 0.78 PDPK1 (0.62) ESR1ESR2CYP11B1CYP11B2CYP17A1
SCHEMBL16905443 0.78 CYP1A2 (0.62) ESR1ESR2CYP11B1CYP11B2CYP17A1
SCHEMBL239390 0.78 CYP2A6 (0.54) NPC1RAB9A
SCHEMBL30502940 0.78 CYP2A6 (0.54) NPC1RAB9A
SCHEMBL30304006 0.77 ESR1 (0.73) ESR1ESR2CYP11B1CYP11B2CYP17A1
SCHEMBL16107069 0.77 ESR1 (0.73) ESR1ESR2CYP11B1CYP11B2CYP17A1
SCHEMBL16968057 0.76 DYRK1A (0.52) CYP19A1CLK4MAP4K4TYK2CLK1
SCHEMBL15618458 0.76 HSD17B1 (0.54) CYP11B1CYP11B2CYP17A1CYP19A1NPC1
SCHEMBL15507438 0.76 CYP2A6 (0.62) CYP11B1CYP11B2CYP17A1CYP19A1CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076027-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LT MATERIALS CO LTD (KR) 2026-03-12 US disclosed
EP-4707356-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2026-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076027-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CYC1, CRY2 ESR1 314/4885ESR2 765/4885CYP11B1 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.