Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.68 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987015 | 1.00 | VCAM1 (0.68) | VCAM1GSK3BMEN1KMT2AALDH1A1 | |
| SCHEMBL12515184 | 0.87 | MEN1 (0.59) | VCAM1GSK3BMEN1KMT2AALDH1A1 | |
| SCHEMBL240083 | 0.87 | VCAM1 (0.72) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4175676 | 0.85 | VCAM1 (0.70) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6740307 | 0.85 | VCAM1 (0.70) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7315029 | 0.85 | VCAM1 (0.60) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29033969 | 0.84 | VCAM1 (0.68) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28386123 | 0.84 | VCAM1 (0.68) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12429089 | 0.84 | VCAM1 (0.68) | VCAM1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18833711 | 0.84 | VCAM1 (0.68) | VCAM1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936136-B | Novel imidazopyrimidine compounds and uses thereof | 儿童医学中心公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20230285378-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220242867-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-08-04 | — | — | US | disclosed |
| CN-111936136-A | Novel imidazopyrimidine compounds and uses thereof | 儿童医学中心公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-1999040088-A1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS, IN PARTICULAR AS UROKINASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-08-12 | — | — | WO | disclosed |
| EP-0008047-B1 | 5(6)-(2-AMINO-5-THIAZOLOYL)BENZIMIDAZOLE-2-CARBAMIC ACID ESTERS AND THEIR SALTS, THEIR PREPARATION AND USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | disclosed |
| US-4386097-A | Benzimidazoles, processes for their preparation and pharmaceutical preparations containing such compounds | CIBA-GEIGY CORPORATION (US) | 1983-05-31 | — | — | US | disclosed |
| US-4297365-A | Benzimidazoles and pharmaceutical preparations containing such compounds | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |
| US-4243806-A | ANTIALLERGENS; ANTIHISTAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-01-06 | — | — | US | disclosed |
| US-4208481-A | BIOSYNTHESIS | E. R. SQUIBB & SONS, INC. (US) | 1980-06-17 | — | — | US | disclosed |
| EP-0008047-A1 | 5(6)-(2-Amino-5-thiazoloyl)benzimidazole-2-carbamic acid esters and their salts, their preparation and use, and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-02-20 | — | — | EP | disclosed |
| US-4179505-A | ANTIALLERGENS; ANTIHISTAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285378-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | VCAM1 931/4885GSK3B 665/4885MEN1 4681/4885 |
| US-20220242867-A1 | NOVEL IMIDAZOPYRIMIDINE COMPOUNDS AND USES THEREOF | HLA-DRB1, NOD1, HLA-A | VCAM1 3780/4885GSK3B 124/4885MEN1 3209/4885 |
| US-11730810-B2 | Composition comprising an antigen and a substituted imidazo[1,2-a]pyrimidine for enhancing human immune response | CD4, MYD88, STING1 | VCAM1 3554/4885GSK3B 4853/4885MEN1 4579/4885 |
| US-11673891-B2 | Imidazopyrimidine compounds and uses thereof | HLA-DRB1, HLA-A, IRF3 | VCAM1 3847/4885GSK3B 151/4885MEN1 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.