Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2394873 | 0.89 | PGR (0.45) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL2395415 | 0.88 | PGR (0.45) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL1844371 | 0.85 | PGR (0.44) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL2394160 | 0.85 | PGR (0.43) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL5038555 | 0.83 | PGR (0.46) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL1315515 | 0.81 | PGR (0.41) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL2398052 | 0.80 | PGR (0.46) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL2393468 | 0.80 | NR3C1 (0.44) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL2395746 | 0.79 | NR3C1 (0.44) | PGRNR3C1ARESR1ESR2 | |
| SCHEMBL2392224 | 0.79 | NR3C1 (0.45) | PGRNR3C1ARESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420635-B2 | Method for preventing or treating a glucocorticoid receptor-related disease | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2013-04-16 | — | — | US | claimed |
| US-8017775-B2 | 1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-13 | — | — | US | claimed |