Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 6/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23940219 | 0.86 | TSHR (0.54) | ALDH1A1SMN1; SMN2NPC1HPGDMEN1 | |
| SCHEMBL15458754 | 0.82 | SMN1; SMN2 (0.51) | CREBBPALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL3924368 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LMNAL3MBTL1KDM4EHTT | |
| SCHEMBL6005094 | 0.81 | MAOB (0.61) | CREBBPEP300ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL23940249 | 0.80 | BRD4 (0.55) | CREBBPALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL23940153 | 0.80 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL23940202 | 0.78 | LMNA (0.46) | CREBBPALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL22810540 | 0.78 | CREBBP (0.51) | CREBBPEP300ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13209353 | 0.78 | NR4A2 (0.65) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23940222 | 0.77 | KMT2A (0.47) | CREBBPALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | TYK2, JAK3, JAK1 | CREBBP 1002/4885EP300 2236/4885ALDH1A1 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.