Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23940249 | 0.85 | BRD4 (0.55) | CREBBPLMNAALDH1A1HDAC1HDAC2 | |
| SCHEMBL23940202 | 0.83 | LMNA (0.46) | SMN1; SMN2CREBBPLMNAALDH1A1HDAC1 | |
| SCHEMBL23940223 | 0.82 | HDAC1 (0.57) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL23940153 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL23940243 | 0.81 | ALDH1A1 (0.59) | KMT2AMEN1SMN1; SMN2CREBBPPOLB | |
| SCHEMBL23940144 | 0.80 | CREBBP (0.49) | CREBBPLMNAALDH1A1HDAC1HDAC2 | |
| SCHEMBL23940236 | 0.77 | CREBBP (0.51) | KMT2AMEN1SMN1; SMN2CREBBPLMNA | |
| SCHEMBL15458754 | 0.75 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2CREBBPLMNA | |
| SCHEMBL3924368 | 0.75 | ALDH1A1 (0.53) | LMNAPOLBALDH1A1MAPT | |
| SCHEMBL13209353 | 0.75 | NR4A2 (0.65) | KMT2AMEN1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323966-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | TYK2, JAK3, JAK1 | KMT2A 1521/4885MEN1 3877/4885SMN1; SMN2 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.