Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499319 | 0.81 | HTR1A (0.51) | CYP4F2CYP4A11ESR1ESR2HTR1A | |
| SCHEMBL16650295 | 0.81 | CA2 (0.38) | CYP4F2CYP4A11ESR1ESR2CA2 | |
| SCHEMBL27760165 | 0.81 | HTR1A (0.51) | CYP4F2CYP4A11ESR1ESR2HTR1A | |
| SCHEMBL13979873 | 0.81 | HTR1A (0.51) | CYP4F2CYP4A11ESR1ESR2HTR1A | |
| SCHEMBL23940440 | 0.78 | TDP1 (0.38) | CYP4F2CYP4A11ESR1ESR2HTR1A | |
| SCHEMBL14271049 | 0.76 | CA2 (0.55) | CA2CYP1A2CYP2D6ALPGCYP2C19 | |
| SCHEMBL6051185 | 0.76 | CA2 (0.55) | CA2CYP1A2CYP2D6ALPGCYP2C19 | |
| SCHEMBL19931577 | 0.76 | ITGB3 (0.41) | CYP4F2CYP4A11CA2SMN1; SMN2ITGB3 | |
| SCHEMBL22663014 | 0.76 | TDP1 (0.55) | CYP4F2CYP4A11ITGB3ITGA2BDRD2 | |
| SCHEMBL16650443 | 0.75 | PNMT (0.46) | SMN1; SMN2ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |