Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697459 | 0.77 | ACLY (0.36) | KCNH2MPOADRB2ADRB1 | |
| SCHEMBL12397446 | 0.77 | ACLY (0.36) | KCNH2MPOADRB2ADRB1 | |
| SCHEMBL23940684 | 0.77 | ACLY (0.36) | KCNH2MPOADRB2ADRB1 | |
| SCHEMBL17011675 | 0.73 | ACLY (0.35) | KCNH2MPO | |
| SCHEMBL17011674 | 0.73 | ACLY (0.35) | KCNH2MPO | |
| SCHEMBL20006876 | 0.73 | KCNH2 (0.38) | KCNH2MPOADRB2ADRB1 | |
| SCHEMBL19174152 | 0.70 | BCHE (0.42) | MPO | |
| SCHEMBL24299331 | 0.68 | MPO (0.50) | MPO | |
| SCHEMBL12520531 | 0.68 | TYR (0.56) | MPO | |
| SCHEMBL19174337 | 0.67 | ADRB2 (0.45) | KCNH2MPOADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |