Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006770 | 0.87 | HTR1D (0.52) | HTR1DHTR1BOPRK1OPRM1OPRL1 | |
| SCHEMBL23940661 | 0.85 | HTR1D (0.48) | HTR1DHTR1BOPRK1OPRM1OPRL1 | |
| SCHEMBL24317059 | 0.83 | HTR1D (0.49) | HTR1DHTR1BOPRK1OPRM1OPRL1 | |
| SCHEMBL20006885 | 0.77 | HTR1D (0.51) | HTR1DHTR1BOPRK1OPRM1PRMT5 | |
| SCHEMBL20006880 | 0.76 | HTR1D (0.45) | HTR1DHTR1BOPRK1OPRM1OPRL1 | |
| SCHEMBL20006982 | 0.75 | HTR1D (0.49) | HTR1DHTR1BOPRK1OPRM1PRMT5 | |
| SCHEMBL13533180 | 0.72 | SLC6A4 (0.43) | HTR1DHTR1BOPRK1OPRM1OPRL1 | |
| SCHEMBL14069704 | 0.71 | HTR1A (0.59) | HTR1DHTR1BOPRK1OPRM1ADRA2A | |
| SCHEMBL7273416 | 0.71 | HTR1D (0.40) | HTR1DHTR1BOPRK1OPRM1PRMT5 | |
| SCHEMBL6950353 | 0.71 | OPRK1 (0.62) | HTR1DHTR1BOPRK1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |