Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006770 | 0.84 | HTR1D (0.52) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL23940661 | 0.83 | HTR1D (0.48) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL23940696 | 0.83 | HTR1D (0.48) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL20006880 | 0.81 | HTR1D (0.45) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL24316813 | 0.75 | HTR1D (0.39) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL18900425 | 0.74 | ALDH1A1 (0.35) | HTR1DHTR1BOPRK1MCHR1ALDH1A1 | |
| SCHEMBL20006885 | 0.74 | HTR1D (0.51) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL20006982 | 0.72 | HTR1D (0.49) | HTR1DHTR1BPRMT5KCNH2OPRM1 | |
| SCHEMBL13533180 | 0.70 | SLC6A4 (0.43) | HTR1DHTR1BKCNH2OPRM1OPRK1 | |
| SCHEMBL7273416 | 0.69 | HTR1D (0.40) | HTR1DHTR1BPRMT5KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |