SCHEMBL23944610

SCHEMBL23944610

COc1cc2ccccc2nc1-c1c(Br)ccc(Cl)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 5/20 0.50
NQO2 P16083 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
AMY1A P0DUB6 2/20 0.37
ACHE P22303 1/20 0.37
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 2/20 0.37
PDE10A Q9Y233 1/20 0.37
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.36
BLM P54132 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23944624 0.80 BTK (0.46) TLR8NQO2MEN1KMT2AAMY1A
SCHEMBL23944899 0.78 TLR8 (0.54) TLR8NQO2MEN1KMT2AACHE
SCHEMBL9590284 0.74 TLR8 (0.67) TLR8NQO2MEN1KMT2AACHE
SCHEMBL23944626 0.71 MAOA (0.37) TLR8SMN1; SMN2
SCHEMBL23944609 0.71 MAOA (0.37) TLR8SMN1; SMN2
SCHEMBL10641295 0.69 L3MBTL1 (0.61) TLR8NQO2ALDH1A1SMN1; SMN2HPGD
SCHEMBL31529366 0.69 L3MBTL1 (0.61) TLR8NQO2ALDH1A1SMN1; SMN2HPGD
SCHEMBL12969936 0.68 TLR8 (0.62) TLR8NQO2MEN1KMT2AACHE
SCHEMBL7045347 0.68 TLR8 (1.00) TLR8NQO2MEN1KMT2AALDH1A1
SCHEMBL9589202 0.68 TLR8 (0.62) TLR8NQO2MEN1KMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021210910-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-10-21 WO disclosed