SCHEMBL23944899

SCHEMBL23944899

COc1cc2ccccc2nc1-c1c(N)cccc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.54
HSP90AA1 P07900 3/20 0.45
HSP90AB1 P08238 2/20 0.45
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
GLA P06280 2/20 0.42
HPGD P15428 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
PTBP1 P26599 1/20 0.42
RCE1 Q9Y256 1/20 0.42
NQO2 P16083 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ACHE P22303 1/20 0.39
PDE10A Q9Y233 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23944699 0.78 BTK (0.46) TLR8HSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL23944610 0.78 TLR8 (0.50) TLR8KMT2AMEN1ALDH1A1KDM4E
SCHEMBL9590284 0.77 TLR8 (0.67) TLR8KMT2AMEN1ALDH1A1KDM4E
SCHEMBL23944928 0.75 PDGFRB (0.55) TLR8HSP90AA1HSP90AB1ALDH1A1KDM4E
SCHEMBL23944919 0.73 PDGFRB (0.55) TLR8HSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL31529366 0.71 L3MBTL1 (0.61) TLR8ALDH1A1KDM4EGLAHPGD
SCHEMBL10641295 0.71 L3MBTL1 (0.61) TLR8ALDH1A1KDM4EGLAHPGD
SCHEMBL7045347 0.71 TLR8 (1.00) TLR8KMT2AMEN1ALDH1A1KDM4E
SCHEMBL12969936 0.71 TLR8 (0.62) TLR8KMT2AMEN1ALDH1A1KDM4E
SCHEMBL31134115 0.70 ALDH1A1 (0.65) TLR8HSP90AA1HSP90AB1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402928-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2022-12-22 US disclosed
WO-2021210910-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402928-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, CRY1, CRY2 TLR8 4272/4885HSP90AA1 4312/4885HSP90AB1 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.