Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14892490 | 0.87 | ALDH1A1 (0.57) | SIRT6ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14669420 | 0.87 | MAPT (0.53) | SIRT6ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1552158 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL1552598 | 0.85 | MAPT (0.54) | SIRT6ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3180322 | 0.83 | BRD4 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14892358 | 0.82 | MAPT (0.50) | SIRT6ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14669416 | 0.82 | ALDH1A1 (0.48) | SIRT6ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4258177 | 0.82 | NPBWR1 (0.58) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL1551610 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5332939 | 0.81 | ALDH1A1 (0.48) | SIRT6ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210324198-A1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | Life Technologies Corporation | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210324198-A1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | SRI, SI, IK | SIRT6 155/4885ALDH1A1 1849/4885MAPT 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.