Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 4/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669416 | 0.99 | ALDH1A1 (0.48) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL5332122 | 0.84 | PRMT5 (0.46) | MAPTNPC1RAB9AALK | |
| SCHEMBL1552598 | 0.83 | MAPT (0.54) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL14669420 | 0.82 | MAPT (0.53) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL21753620 | 0.81 | MAPT (0.61) | ALDH1A1MAPTSIRT6MAPK1L3MBTL1 | |
| SCHEMBL23945280 | 0.81 | SIRT6 (0.54) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL14892358 | 0.80 | MAPT (0.50) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL4258177 | 0.78 | NPBWR1 (0.58) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL14892490 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD | |
| SCHEMBL14669417 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TOP1TOP2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |