SCHEMBL23946247

SCHEMBL23946247

Cc1nc(-c2ccccc2)c2cccc(-c3ccccc3-c3ccccc3)c2n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.42
ENPP1 P22413 2/20 0.40
DHODH Q02127 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C8 P10632 1/20 0.39
CYP2C9 P11712 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NUDT1 P36639 3/20 0.38
NTRK1 P04629 2/20 0.38
ADORA2A P29274 2/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
NTRK3 Q16288 1/20 0.36
KDM1A O60341 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
METAP2 P50579 1/20 0.36
TNF P01375 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23946283 0.93 CRHR1 (0.47) CRHR1ENPP1DHODHCYP3A4CYP2C8
SCHEMBL23946331 0.90 DHODH (0.45) CRHR1ENPP1DHODHCYP3A4CYP2C8
SCHEMBL23946251 0.84 CRHR1 (0.43) CRHR1ENPP1DHODHCYP3A4CYP2C8
SCHEMBL23946255 0.83 CRHR1 (0.36) CRHR1L3MBTL1NUDT1NTRK1KDM4E
SCHEMBL23946338 0.83 CRHR1 (0.38) CRHR1L3MBTL1NUDT1NTRK1KDM4E
SCHEMBL24689399 0.80 ADORA2A (0.53) DHODHNUDT1ADORA2AKDM4EALDH1A1
SCHEMBL3243131 0.79 PARP1 (0.48) DHODHCYP3A4CYP2C9L3MBTL1NUDT1
SCHEMBL13312410 0.78 CRHR1 (0.48) CRHR1ENPP1DHODHCYP3A4CYP2C8
SCHEMBL23946321 0.77 L3MBTL1 (0.39) CRHR1L3MBTL1NUDT1NTRK1KDM4E
SCHEMBL23946256 0.77 L3MBTL1 (0.39) ENPP1L3MBTL1NUDT1NTRK1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 CRHR1 3261/4885ENPP1 1682/4885DHODH 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.