SCHEMBL3243131

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23946283	0.81	CRHR1 (0.47)	KDM4ECYP2C9CYP3A4L3MBTL1NTRK1
	SCHEMBL23946247	0.79	CRHR1 (0.42)	KDM4ECYP2C9CYP3A4MAPTL3MBTL1
	SCHEMBL23946331	0.79	DHODH (0.45)	KDM4ECYP2C9CYP3A4L3MBTL1NTRK1
	SCHEMBL19169192	0.78	MAOA (0.46)	CYP1A2KDM4ECYP3A4MAPTL3MBTL1
	SCHEMBL3664754	0.78	ESR1 (0.50)	PARP1ESR1L3MBTL1NUDT1
	SCHEMBL3242174	0.77	PARP1 (0.47)	PARP1TNKSTNKS2CYP1A2ESR1
	SCHEMBL7011032	0.77	PARP1 (0.50)	PARP1TNKSTNKS2CYP1A2KDM4E
	SCHEMBL23946251	0.76	CRHR1 (0.43)	KDM4ECYP2C9CYP3A4MAPTL3MBTL1
	SCHEMBL19169646	0.75	MAOA (0.44)	CYP1A2KDM4ECYP2C19CYP3A4MAPT
	SCHEMBL1773091	0.74	NUDT1 (0.60)	KDM4EKMT2AMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.