Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23946283 | 0.97 | CRHR1 (0.47) | DHODHCYP3A4CYP2C8CYP2C9CRHR1 | |
| SCHEMBL23946251 | 0.91 | CRHR1 (0.43) | DHODHCYP3A4CYP2C8CYP2C9CRHR1 | |
| SCHEMBL23946247 | 0.90 | CRHR1 (0.42) | DHODHCYP3A4CYP2C8CYP2C9CRHR1 | |
| SCHEMBL23946303 | 0.83 | KDM4E (0.38) | DHODHCRHR1ADORA2AKDM4EALDH1A1 | |
| SCHEMBL13312410 | 0.81 | CRHR1 (0.48) | DHODHCYP3A4CYP2C8CYP2C9CRHR1 | |
| SCHEMBL19169646 | 0.81 | MAOA (0.44) | DHODHCYP3A4ADORA2AKDM4EALDH1A1 | |
| SCHEMBL23946321 | 0.81 | L3MBTL1 (0.39) | CRHR1KDM4EALDH1A1L3MBTL1TDP1 | |
| SCHEMBL23946255 | 0.80 | CRHR1 (0.36) | CRHR1KDM4EALDH1A1L3MBTL1NUDT1 | |
| SCHEMBL23946294 | 0.80 | CRHR1 (0.45) | DHODHCYP3A4CYP2C8CYP2C9CRHR1 | |
| SCHEMBL23946301 | 0.80 | CRHR1 (0.36) | DHODHCRHR1KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210328153-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | IDO1, IDO2, AZI2 | DHODH 824/4885CYP3A4 222/4885CYP2C8 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.