Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 16/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21616795 | 1.00 | MEN1 (0.56) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL28798546 | 1.00 | MEN1 (0.56) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL7132314 | 1.00 | MEN1 (0.56) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL28385599 | 1.00 | MEN1 (0.56) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL8450143 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL16307692 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL27921181 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL31501079 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395819 | 0.97 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2399324 | 0.97 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013181345-A2 | SYNTHESIS OF POLYMERIC IONIC LIQUIDS USING A PHOTOCHEMICAL POLYMERIZATION PROCESS | THE UNIVERSITY OF TOLEDO (US) | 2013-12-05 | — | — | WO | claimed |
| US-20110236295-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2011-09-29 | — | — | US | claimed |
| WO-2010017563-A1 | POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | claimed |
| US-20250135435-A1 | SYSTEM FOR BATCH SCALE PRODUCTION OF EXTRACTION SORBENTS WITH 3D PRINTING AND ASSOCIATED METHOD OF USE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2025-05-01 | — | — | US | disclosed |
| US-10752648-B2 | Magnetic ionic liquids, methods of making and uses thereof as solvents in the extraction and preservation of nucleic acids | THE UNIVERSITY OF TOLEDO (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190194643-A1 | Magnetic Ionic Liquids, Methods of Making and Uses Thereof as Solvents in the Extraction and Preservation of Nucleic Acids | THE UNIVERSITY OF TOLEDO (US) | 2019-06-27 | — | — | US | disclosed |
| US-10280416-B1 | Magnetic ionic liquids, methods of making and uses thereof as solvents in the extraction and preservation of nucleic acids | THE UNIVERSITY OF TOLEDO (US) | 2019-05-07 | — | — | US | disclosed |
| US-9782748-B2 | Synthesis of polymeric ionic liquids using a photochemical polymerization process | THE UNIVERSITY OF TOLEDO (US) | 2017-10-10 | — | — | US | disclosed |
| US-9782746-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160114309-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-04-28 | — | — | US | disclosed |
| US-9249261-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150119231-A1 | Synthesis of Polymeric Ionic Liquids Using a Photochemical Polymerization Process | THE UNIVERSITY OF TOLEDO (US) | 2015-04-30 | — | — | US | disclosed |
| US-8734673-B2 | Boron selective ionic liquids and polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2014-05-27 | — | — | US | disclosed |
| WO-2013181345-A2 | SYNTHESIS OF POLYMERIC IONIC LIQUIDS USING A PHOTOCHEMICAL POLYMERIZATION PROCESS | THE UNIVERSITY OF TOLEDO (US) | 2013-12-05 | — | — | WO | disclosed |
| US-20120111796-A1 | Boron Selective Ionic Liquids and Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110236295-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2011-09-29 | — | — | US | disclosed |
| WO-2010017564-A1 | BORON SELECTIVE IONIC LIQUIDS AND POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010017563-A1 | POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752648-B2 | Magnetic ionic liquids, methods of making and uses thereof as solvents in the extraction and preservation of nucleic acids | POLRMT, HNRNPH3, HNRNPL | MEN1 154/4885HSP90AA1 3428/4885KMT2A 1090/4885 |
| US-20120111796-A1 | Boron Selective Ionic Liquids and Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | BCCIP, SLC6A12, BOLA2; BOLA2B | MEN1 1196/4885HSP90AA1 4401/4885KMT2A 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.