Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.48 |
| ▸ | SYK | P43405 | 4/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.44 |
| ▸ | MERTK | Q12866 | 3/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748532 | 0.93 | PDE4B (0.44) | PDE4BSYKTYRO3MERTKFLT3 | |
| SCHEMBL15249748 | 0.91 | SYK (0.51) | PDE4BSYKMERTKPPARGMEN1 | |
| SCHEMBL26161013 | 0.88 | SYK (0.49) | SYKMERTKPPARGMEN1KMT2A | |
| SCHEMBL1226594 | 0.88 | MEN1 (0.49) | SYKMERTKPPARGMEN1KMT2A | |
| SCHEMBL26931049 | 0.86 | MERTK (0.57) | SYKTYRO3MERTKFLT3GAS6 | |
| SCHEMBL26931042 | 0.86 | MERTK (0.57) | SYKTYRO3MERTKFLT3GAS6 | |
| SCHEMBL29502000 | 0.84 | ALDH1A1 (0.57) | PDE4BSYKMAPK1MEN1KMT2A | |
| SCHEMBL4157935 | 0.84 | ALDH1A1 (0.57) | PDE4BSYKMAPK1MEN1KMT2A | |
| SCHEMBL25057374 | 0.82 | SYK (0.41) | PDE4BSYKMERTKPPARGMEN1 | |
| SCHEMBL23948231 | 0.82 | MERTK (0.44) | PDE4BSYKMERTKPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027034-A | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114315834-B | Imidazolone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117321057-A | Preparation process of imidazolone derivative and intermediate thereof | 成都百裕制药股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| WO-2023025160-A1 | PREPARATION PROCESS FOR IMIDAZOLINONE DERIVATIVE, AND INTERMEDIATE THEREOF | 成都百裕制药股份有限公司 | 2023-03-02 | — | — | WO | disclosed |
| EP-4137491-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |
| CN-114315834-A | Imidazolidinone derivatives and their use in medicaments | 成都百裕制药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021209055-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | SYMPK, PAICS, CYP2C9 | PDE4B 1193/4885SYK 601/4885TYRO3 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.