SCHEMBL23949487

SCHEMBL23949487

CCOC(=O)C1Nc2ccc(C(=O)O)cc2C2C=CCC12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 1.00
POLB P06746 9/20 1.00
MEN1 O00255 9/20 1.00
GAA P10253 4/20 1.00
L3MBTL1 Q9Y468 6/20 0.84
HSPA1A P0DMV8 7/20 0.74
PTPN7 P35236 7/20 0.74
ALDH1A1 P00352 5/20 0.74
MAPT P10636 5/20 0.74
GAPDH P04406 4/20 0.74
MASP2 O00187 3/20 0.74
HPGD P15428 3/20 0.74
KDM4E B2RXH2 3/20 0.74
MCL1 Q07820 2/20 0.74
ALOX15 P16050 2/20 0.74
BRCA1 P38398 2/20 0.74
RECQL P46063 2/20 0.74
BLM P54132 2/20 0.74
HSD17B10 Q99714 2/20 0.74
THRB P10828 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26458981 1.00 KMT2A (1.00) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL10053590 0.88 POLB (0.80) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL6215376 0.86 POLB (0.77) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL13856706 0.85 PTPN7 (1.00) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL1066515 0.85 PTPN7 (1.00) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL10022369 0.85 POLB (0.75) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL17211738 0.84 HSPA1A (0.81) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL2808722 0.84 PTPN7 (1.00) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL29415450 0.84 PTPN7 (1.00) KMT2APOLBMEN1GAAL3MBTL1
SCHEMBL23949935 0.79 KMT2A (1.00) KMT2APOLBMEN1GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021209689-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SWEET POTATO AGAINST SWEET POTATO PATHOGENIC VIRUSES HELSINGIN YLIOPISTO (FI) 2021-10-21 WO disclosed