Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23955974 | 0.88 | PTGS2 (0.34) | PTGS2PTGS1 | |
| SCHEMBL23955975 | 0.72 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL23956002 | 0.72 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL23955976 | 0.72 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL21840751 | 0.71 | CYP19A1 (0.32) | — | |
| SCHEMBL29960251 | 0.71 | CYP19A1 (0.32) | — | |
| SCHEMBL23257919 | 0.70 | DRD2 (0.33) | — | |
| SCHEMBL23955996 | 0.70 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL22148949 | 0.65 | — | — | |
| SCHEMBL23088751 | 0.65 | PTGS2 (0.36) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | RPS10, ARL1, OR10J3 | PTGS2 3692/4885PTGS1 3796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.