Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956002 | 0.87 | PTGS2 (0.33) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL23955977 | 0.82 | — | — | |
| SCHEMBL23955976 | 0.74 | PTGS2 (0.42) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL23955973 | 0.72 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL23955974 | 0.72 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL21840762 | 0.72 | KDR (0.30) | — | |
| SCHEMBL29960999 | 0.72 | KDR (0.30) | — | |
| SCHEMBL23955996 | 0.71 | PTGS2 (0.40) | PTGS2MTNR1AMTNR1B | |
| SCHEMBL23258574 | 0.68 | — | — | |
| SCHEMBL22148950 | 0.66 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | RPS10, ARL1, OR10J3 | PTGS2 3692/4885MTNR1A 1335/4885MTNR1B 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.