⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23172781 | 0.83 | — | — | |
| SCHEMBL23172666 | 0.82 | — | — | |
| SCHEMBL23172606 | 0.75 | — | — | |
| SCHEMBL22148950 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL23258763 | 0.72 | BRD4 (0.31) | — | |
| SCHEMBL23257919 | 0.71 | DRD2 (0.33) | — | |
| SCHEMBL23257932 | 0.71 | — | — | |
| SCHEMBL23258063 | 0.70 | GPR3 (0.31) | — | |
| SCHEMBL23955975 | 0.68 | PTGS2 (0.33) | — | |
| SCHEMBL23141288 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427608-B2 | Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2022-08-30 | — | — | US | disclosed |
| US-20210115080-A1 | DIHYDROCARBYL-SILYL-BRIDGED-1,3 DISUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-04-22 | — | — | US | disclosed |