Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957302 | 0.90 | NLRP3 (0.52) | NLRP3CA2 | |
| SCHEMBL23957301 | 0.90 | NLRP3 (0.50) | NLRP3CA2 | |
| SCHEMBL19518995 | 0.89 | NLRP3 (0.65) | NLRP3CA2 | |
| SCHEMBL23957223 | 0.88 | NLRP3 (0.47) | NLRP3CA2 | |
| SCHEMBL23957221 | 0.88 | NLRP3 (0.47) | NLRP3CA2 | |
| SCHEMBL19475370 | 0.86 | NLRP3 (0.54) | NLRP3CA2 | |
| SCHEMBL19519058 | 0.86 | NLRP3 (0.66) | NLRP3CA2 | |
| SCHEMBL19518977 | 0.84 | NLRP3 (0.49) | NLRP3CA2 | |
| SCHEMBL19518992 | 0.82 | NLRP3 (0.54) | NLRP3CA2 | |
| SCHEMBL19518981 | 0.81 | NLRP3 (0.47) | NLRP3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332020-A1 | PHENYLSULFONYLUREA DERIVATIVES USEFUL AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332020-A1 | PHENYLSULFONYLUREA DERIVATIVES USEFUL AS NLRP3 INHIBITORS | NLRP3, NOD1, PYCARD | NLRP3 1/4885CA2 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.