Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110764 | 0.84 | HTT (0.58) | ALDH1A1KDM4EGAAMAPTCXCR2 | |
| SCHEMBL8302266 | 0.77 | PRKCI (0.45) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL23013861 | 0.74 | NOS3 (0.39) | ALDH1A1KDM4EGAA | |
| SCHEMBL4852724 | 0.73 | MAPT (0.58) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL634467 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL2312770 | 0.72 | IKBKB (0.49) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL11900810 | 0.71 | GAA (0.76) | ALDH1A1KDM4EGAAMAPTCXCR2 | |
| SCHEMBL7179632 | 0.70 | TMPRSS4 (0.66) | ALDH1A1KDM4EMAPTCXCR2CXCR1 | |
| SCHEMBL13162545 | 0.69 | CYP11B2 (0.64) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL13610402 | 0.68 | GAA (1.00) | ALDH1A1KDM4EGAAMAPTCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |