SCHEMBL13610402

SCHEMBL13610402

N#Cc1ccc(Nc2ccccc2)c(N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 1.00
KDM4E B2RXH2 7/20 1.00
ALDH1A1 P00352 7/20 1.00
MAPT P10636 8/20 0.63
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
HPGD P15428 3/20 0.63
LMNA P02545 2/20 0.63
HTT P42858 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
GFER P55789 2/20 0.53
HSD17B10 Q99714 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
THRB P10828 1/20 0.53
CXCR2 P25025 3/20 0.51
CXCR1 P25024 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29642859 1.00 GAA (1.00) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL11900810 0.86 GAA (0.76) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL16197958 0.84 KDM4E (0.72) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL12407368 0.83 KDM4E (0.71) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL2644882 0.83 GAA (0.70) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL1761791 0.83 KDM4E (0.70) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL13750111 0.81 ALDH1A1 (0.69) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL28248993 0.81 KDM4E (0.68) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL12655635 0.80 KDM4E (0.66) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL5645453 0.79 ALDH1A1 (0.66) GAAKDM4EALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-05-01 US disclosed
CN-114933614-A Organic electroluminescent material and device 环球展览公司 2022-08-23 CN disclosed
CN-105820122-B Organic electroluminescent material and device 环球展览公司 2022-05-17 CN disclosed
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 US disclosed
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 US disclosed
CN-105820122-A Organic electroluminescent material and device 环球展览公司 2016-08-03 CN disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 US disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 US disclosed
US-7622594-B2 Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2009-11-24 US disclosed
US-20070060633-A1 Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OPRD1 GAA 4278/4885KDM4E 1990/4885ALDH1A1 1023/4885
US-20070060633-A1 Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof NR3C1, MC2R, NR3C2 GAA 1264/4885KDM4E 4087/4885ALDH1A1 2756/4885
US-10418569-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP2 GAA 2911/4885KDM4E 4426/4885ALDH1A1 1620/4885
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 GAA 2911/4885KDM4E 4426/4885ALDH1A1 1620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.