Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312770 | 0.85 | IKBKB (0.49) | KDM4EKMT2AGFERRXFP1MCL1 | |
| SCHEMBL3609438 | 0.85 | XDH (0.49) | KDM4EKMT2AGFERRXFP1MCL1 | |
| SCHEMBL1482937 | 0.84 | KDM4E (0.67) | KDM4EKMT2AGFERRXFP1MCL1 | |
| SCHEMBL14739736 | 0.83 | ALDH1A1 (0.40) | KDM4EKMT2AGFERRXFP1MCL1 | |
| SCHEMBL4852724 | 0.82 | MAPT (0.58) | KDM4EKMT2AMEN1USP2POLB | |
| SCHEMBL3157619 | 0.82 | XDH (0.53) | KMT2ATDP1MEN1POLBALDH1A1 | |
| SCHEMBL22637148 | 0.81 | KDM4E (0.57) | KDM4EKMT2AGFERRXFP1MCL1 | |
| SCHEMBL9043331 | 0.79 | RAB9A (0.42) | KDM4EKMT2AGFERRXFP1POLB | |
| SCHEMBL4842734 | 0.79 | ALDH1A1 (0.57) | KDM4ERXFP1POLBMAPTGLA | |
| SCHEMBL2033094 | 0.79 | BRAF (0.42) | KDM4EKMT2AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043563-A1 | PEPTIDE TARGETING SOMATOSTATIN RECEPTOR, DRUG CONJUGATE AND USE THEREOF | 主流源生物科技(上海)有限公司 | 2025-03-06 | — | — | WO | claimed |
| CN-122036604-A | Compound and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| WO-2026099895-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | PI INDUSTRIES LTD. (IN) | 2026-05-15 | — | — | WO | disclosed |
| WO-2026099895-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | PI INDUSTRIES LTD. (IN) | 2026-05-15 | — | — | WO | disclosed |
| US-20250154152-A1 | INHIBITORS OF NAEGLERIA FOWLERI | CLEMSON UNIVERSITY | 2025-05-15 | — | — | US | disclosed |
| CN-119977893-A | Preparation method and application of sulfonamide compound for antagonizing NOD1 | 清华大学 | 2025-05-13 | — | — | CN | disclosed |
| WO-2025056012-A1 | NEUTROPHIL ELASTASE INHIBITOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638624-A | Neutrophil elastase inhibitor and application thereof | 上海壹迪生物技术有限公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2025043563-A1 | PEPTIDE TARGETING SOMATOSTATIN RECEPTOR, DRUG CONJUGATE AND USE THEREOF | 主流源生物科技(上海)有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-116731017-B | Quinoline and piperidine compound as well as preparation method and application thereof | 海南大学 | 2024-10-01 | — | — | CN | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0912559-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-05-06 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| WO-1998002434-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-01-22 | — | — | WO | disclosed |
| CN-1118595-A | Anthranilic acid derivative | EISAI CO LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3993619-A | AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154152-A1 | INHIBITORS OF NAEGLERIA FOWLERI | SERPINB1, NAMPT, NIT2 | KDM4E 4091/4885KMT2A 4367/4885GFER 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.