Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958201 | 0.86 | ALOX12 (0.43) | TRPV4MAPTLMNA | |
| SCHEMBL24110969 | 0.83 | PIK3CG (0.39) | PIK3CBBTKPIK3CDPIK3R1 | |
| SCHEMBL30025705 | 0.82 | TDO2 (0.45) | ALDH1A2ALDH1A1ALDH1A3PIK3CDMAT2A | |
| SCHEMBL23958242 | 0.82 | TDO2 (0.45) | ALDH1A2ALDH1A1ALDH1A3PIK3CDMAT2A | |
| SCHEMBL24111051 | 0.81 | HTR7 (0.41) | ALDH1A2ALDH1A1ALDH1A3MAT2A | |
| SCHEMBL30103287 | 0.78 | PIK3CD (0.41) | ALDH1A2ALDH1A1ALDH1A3MAPTPIK3CD | |
| SCHEMBL24111001 | 0.78 | PIK3CD (0.41) | ALDH1A2ALDH1A1ALDH1A3MAPTPIK3CD | |
| SCHEMBL24089953 | 0.78 | USP2 (0.40) | ALDH1A2ALDH1A1ALDH1A3MAPTMAT2A | |
| SCHEMBL23958200 | 0.77 | PIK3CD (0.38) | ALDH1A2ALDH1A1ALDH1A3PIK3CD | |
| SCHEMBL30103172 | 0.77 | PIK3CD (0.38) | ALDH1A2ALDH1A1ALDH1A3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-12-16 | — | — | US | disclosed |
| WO-2021215537-A1 | 2-HETEROARYLAMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387967-A1 | 2-HETEROARYL AMINOQUINAZOLINONE DERIVATIVE | CRKL, CLIC4, CLIC1 | TRPV4 3160/4885PIK3CB 3727/4885ALDH1A2 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.