Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.92 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.92 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324835 | 0.81 | KCNH2 (0.72) | CYP2D6KCNH2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17100583 | 0.80 | CYP2D6 (0.71) | CYP2D6KCNH2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18134606 | 0.78 | CYP2D6 (1.00) | CYP2D6KCNH2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL26632300 | 0.78 | MAPK1 (0.68) | CYP2D6KCNH2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL23958389 | 0.78 | KCNH2 (0.57) | CYP2D6KCNH2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL576379 | 0.75 | SIGMAR1 (0.86) | LMNAPOLBKMT2A | |
| SCHEMBL1043563 | 0.75 | SIGMAR1 (0.86) | LMNAPOLBKMT2A | |
| SCHEMBL1044952 | 0.75 | SIGMAR1 (0.86) | LMNAPOLBKMT2A | |
| SCHEMBL577331 | 0.75 | SIGMAR1 (0.86) | LMNAPOLBKMT2A | |
| SCHEMBL3427885 | 0.75 | RAB9A (1.00) | CYP2D6KCNH2LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355597-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | OHIO STATE INNOVATION FOUNDATION | 2023-11-09 | — | — | US | disclosed |
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | OHIO STATE INNOVATION FOUNDATION (US) | 2023-05-30 | — | — | US | disclosed |
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | OHIO STATE INNOVATION FOUNDATION (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210330655-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | OHIO STATE INNOVATION FOUNDATION | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355597-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | FABP2, APC, AP1G1 | CYP2D6 4733/4885KCNH2 4471/4885LMNA 866/4885 |
| US-11660294-B2 | Compounds, compositions, and methods for the treatment and prevention of avian pathogenic E. coli (APEC) | FABP2, APC, AP1G1 | CYP2D6 4733/4885KCNH2 4471/4885LMNA 866/4885 |
| US-20210330655-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT AND PREVENTION OF AVIAN PATHOGENIC E. COLI (APEC) | FABP2, APC, AP1G1 | CYP2D6 4733/4885KCNH2 4471/4885LMNA 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.