Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958812 | 0.88 | CFTR (0.38) | CFTRMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL23958782 | 0.86 | CFTR (0.35) | CFTRMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL23958775 | 0.86 | ADRA1D (0.36) | CFTRMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL23958976 | 0.86 | KDM4E (0.31) | CFTRMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL23958792 | 0.81 | CFTR (0.33) | CFTRMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL23958753 | 0.80 | CFTR (0.32) | CFTR | |
| SCHEMBL23958894 | 0.80 | CFTR (0.34) | CFTRMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL23904891 | 0.77 | PTGS1 (0.33) | CFTRMAPTPOLBALDH1A1KMT2A | |
| SCHEMBL23958813 | 0.76 | CFTR (0.32) | CFTR | |
| SCHEMBL23958779 | 0.75 | MAPT (0.33) | MAPTPOLBKDM4EALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |