Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958976 | 0.92 | KDM4E (0.31) | MAPTCFTRKDM4EALDH1A1POLB | |
| SCHEMBL23958782 | 0.88 | CFTR (0.35) | MAPTCFTRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23958802 | 0.86 | CFTR (0.34) | MAPTCFTRROCK2ROCK1KDM4E | |
| SCHEMBL23958812 | 0.84 | CFTR (0.38) | MAPTCFTRROCK2ROCK1BTK | |
| SCHEMBL23905980 | 0.83 | ADRA1D (0.33) | ADRA1DADRA1AADRA1BMAPTSMN1; SMN2 | |
| SCHEMBL23958753 | 0.82 | CFTR (0.32) | CFTR | |
| SCHEMBL23958792 | 0.81 | CFTR (0.33) | MAPTCFTRSMN1; SMN2ROCK2ROCK1 | |
| SCHEMBL23958894 | 0.81 | CFTR (0.34) | MAPTCFTRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23958797 | 0.80 | CFTR (0.36) | CFTRSMN1; SMN2ROCK2ROCK1ALDH1A1 | |
| SCHEMBL23958739 | 0.76 | TRPV3 (0.34) | CFTRPDE2AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |