Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905332 | 0.82 | SYK (0.37) | CCR1CCR5CCR8PDGFRBPDGFRA | |
| SCHEMBL23904743 | 0.81 | CCR1 (0.52) | ACHECCR1CCR5CCR8ALDH1A1 | |
| SCHEMBL23904742 | 0.81 | PTGS2 (0.41) | ALDH1A1HPGDSCRHR1PDE10A | |
| SCHEMBL23958814 | 0.79 | ALDH1A1 (0.46) | ACHECCR1CCR5CCR8ALDH1A1 | |
| SCHEMBL30006877 | 0.79 | CA12 (0.44) | HPGDSPDGFRBPDGFRA | |
| SCHEMBL23904767 | 0.79 | CA12 (0.44) | HPGDSPDGFRBPDGFRA | |
| SCHEMBL30211241 | 0.78 | HPGDS (0.56) | F2RL3ALDH1A1HPGDSMAPTNQO2 | |
| SCHEMBL23958665 | 0.77 | CYP3A4 (0.43) | ALDH1A1HPGDSMAPTPSMD14 | |
| SCHEMBL23958826 | 0.76 | HPGDS (0.38) | HPGDS | |
| SCHEMBL23905909 | 0.72 | ALDH1A1 (0.50) | CCR1CCR5CCR8ALDH1A1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |